Chemical Hazard Data Commons

The Chemical Hazard Data Commons provides resources to assess and compare human and environmental health hazards of different chemicals, plus tools to collaborate to find safer alternatives. The goal of this effort is to reduce the use of hazardous chemicals and improve the inherent safety of materials and products. Their mission and vision is further detailed in a series of whitepapers.

The Data Commons integrates the following data sources and analyses to show what is known about the hazards of chemicals and facilitate comparisons:

  • Hazard listings – Associations between chemicals and 25 specific human and environmental health endpoints identified by governmental and professional authorities. Largely based on the Healthy Building Network’s Pharos Chemical and Material Library. The Data Commons aggregates over 40 authoritative hazard lists. Sources to keep them up to date. For a list of all the hazard sources and to learn more, check out the Pharos system description. They also include select data that manufacturers have submitted through REACH registration dossiers in addition to the authoritative body listings.
  • Restricted substance lists – Listings of chemicals whose use is restricted and/or managed by regulatory or corporate policy or subject to voluntary program guidance. Data Commons hazard tables reference over 30 restricted substance lists. To learn more, check out the Pharos system description, starting on page 20.
  • Exempt & Positive lists – Listings of chemicals that have been exempted from regulatory actions (such as EPA VOC exemptions) or are preferable for use for certain applications based upon an assessment of lower hazard (such as the EPA SCIL list). Beware, these lists generally have constraints – exemptions of preferences based on a limited set of health endpoints or for limited uses
  • List Screening – The Data Commons is an approved GreenScreen Automator assessing all chemicals in the database against the GreenScreen List Translator to generate LT scores identifying known chemicals of high concern.
  • Hazard assessments – Toxicological assessments using the GreenScreen™ protocol that benchmarks the inherent hazards of chemicals across a broad range of health endpoints. The Data Commons provides access to all GreenScreen assessments published for public use.
  • Identification – Over 85,000 substances are listed in the Data Commons, searchable by over 260,000 CASRNs and synonyms utilizing the NIH PubChem and ChemIDplus databases.
  • Physical properties – chemical formulas and some key physical data are drawn from the NIH PubChem database.
  • Compound groups – The Data Commons is the home of the Compound Group Population Project which creates structural or other definitions for the chemical compound groups referenced by authoritative hazard lists. They use those definitions to associate relevant CASRN with those groups to ensure comprehensive list screening.

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